Research shows early promise of new drug for cancers caused by viruses
Christopher Parsons, MD, Director of the HIV Malignancies Program at LSU Health Sciences Center New Orleans, is the senior author of a paper that is the first to report that specialized fat (lipid)...
View ArticleExisting medicines show promise for treating stomach and bowel cancer
(Medical Xpress)—Stomach and bowel cancer, two of the most common cancers worldwide, could be treated with a class of medicines that are currently used to treat a blood disorder, a Melbourne research...
View ArticleExperimental drug could enhance multiple myeloma and myeloid leukemia therapies
A pre-clinical study led by Virginia Commonwealth University Massey Cancer Center and Department of Internal Medicine researchers suggests that an experimental drug known as dinaciclib could improve...
View ArticleNovel target found for chemotherapy-resistant leukemia cells
Researchers at Children's Hospital Los Angeles have discovered that by targeting a particular receptor, chemotherapy-resistant cancer cells can be killed in an acute form of childhood leukemia,...
View ArticlePine bark substance could be potent melanoma drug
A substance that comes from pine bark is a potential source for a new treatment of melanoma, according to Penn State College of Medicine researchers.
View ArticleResearchers discover a new anticancer compound using accelerated drug...
A team of research scientists from VTT Technical Research Centre of Finland, the University of Turku and the University of Eastern Finland has discovered a previously unknown Cent-1 molecule that kills...
View ArticleFinding the Achilles' Heel of ovarian tumor growth
A team of scientists, led by principal investigator David D. Schlaepfer, PhD, professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine report...
View ArticleAnti-cancer lymphatic drugs show potential
Researchers at the University of Auckland are using zebrafish embryos to investigate potential medicines that will inhibit the spread of some cancers via the lymphatic system.
View ArticleNanoparticle-based invention moves new cancer drugs closer to clinical testing
(Medical Xpress)—Penn State College of Medicine researchers have developed a nanoparticle to deliver a melanoma-fighting drug directly to the cancer.
View ArticleData published on ANG4043, anti-HER2 monoclonal antibody for treatment of...
Angiochem, a clinical stage biotechnology company creating and developing drugs that cross the blood-brain barrier, today announced the publication in Molecular Cancer Therapeutics demonstrating that...
View ArticleRevamped drug may overcome resistance in brain tumours
Cancer Research UK scientists have taken steps to overcome drug resistance in glioblastoma, the most common type of brain tumour in adults, according to research published in Molecular Cancer...
View ArticleProtein predicts breast cancer prognosis
Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating...
View ArticleTrial shows treatment-resistant advanced non-small cell lung cancer responds...
A new drug that targets not only common cancer-causing genetic mutations in patients with non-small cell lung cancer (NSCLC), but also a form of the mutation that causes resistance to treatment, has...
View ArticleThree drugs may be better than one for certain patients with advanced...
Patients with a form of advanced colorectal cancer that is driven by a mutated version of the BRAF gene have limited treatment options available. However, results from a multi-centre clinical trial...
View ArticleResults of new drug, ASP8273, show response in patients with...
In a second presentation looking at new ways of treating non-small cell lung cancer (NSCLC) that has both the EGFR and T790M mutations, researchers will tell the 26th EORTC-NCI-AACR Symposium on...
View ArticleSubcutaneous administration of multispecific antibody makes tumor treatment...
Tumor treatment with multispecific antibodies is significantly more tolerable if administered subcutaneously rather than via the bloodstream, which was the standard procedure until now. This was the...
View ArticleMarine sponge shows tumour-stunting promise
The research, which has been published in the highly-regarded journal Molecular Cancer Therapeutics, suggests that peloruside A—a substance produced by the marine sponge Mycale henscheli, found mostly...
View ArticleScientists uncover process that could drive the majority of cancers
The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or...
View ArticleA new class of drug slows growth of castration-resistant prostate cancer cells
A first-in-class sphingosine kinase 2 inhibitor slowed the growth of castration-resistant prostate cancer cells, in part by inhibiting the enzyme dihydroceramide desaturase (DEGS), but did not kill...
View ArticleScientists create 'guided chemotherapy missiles' that target cancer cells and...
There's a good, bad and ugly to cancer chemotherapy. The good is that the drugs do often effectively kill cancer cells. The bad is that the drugs also damage other quickly dividing cells in the body,...
View ArticleActive agent from the Caribbean sea cucumber could improve treatment for...
Researchers at the Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital have discovered a new option for treating malignant pleural mesothelioma. For the first time in the world,...
View ArticleBiologists link levels of Mena protein to breast cancer cells' sensitivity to...
MIT biologists have identified a new biomarker that can reveal whether patients with a particularly aggressive type of breast cancer will be helped by paclitaxel (commercially known as Taxol), one of...
View ArticleResults from three ground-breaking cancer studies show early benefit to patients
The "revolution in the understanding of cancer at the molecular level" has led to dramatic responses in cancer patients to new therapies that are targeted precisely at their particular type of tumours,...
View ArticleDrug increases survival in dogs with cancer
A breakthrough trial at the University of Minnesota testing a new UMN-developed drug resulted in improved survival rates for dogs diagnosed with a cancer called hemangiosarcoma (HSA). The results were...
View ArticleStudy identifies how cancer cells may develop resistance to FGFR inhibitors
A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has identified a...
View ArticleDrug combination delivered by nanoparticles may help in melanoma treatment
The first of a new class of medication that delivers a combination of drugs by nanoparticle may keep melanoma from becoming resistant to treatment, according to Penn State College of Medicine researchers.
View ArticleKey tool in DNA repair kit found
Breaks in DNA can cause chromosome rearrangements, abnormalities linked to cancer. Now Yale scientists have identified how the molecule DNA2 helps begin the complex process of repairing these breaks.
View ArticleMystery of breast cancer risk gene solved, 20 years after its discovery
More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to...
View ArticleTargeted treatment could prevent spread of pancreatic cancer, heart damage
Researchers at the University of Cincinnati (UC) College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer...
View ArticleResearchers identify a new therapeutic target to fight metastasis in ovarian...
Researchers at Bellvitge Biomedical Research Institute have described a key cellular receptor in the processes of metastasis in ovarian cancer. The finding, published in Molecular Cancer Therapeutics,...
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